Difference between revisions of "Part:BBa K364328:Experience"
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===Ligand=== | ===Ligand=== | ||
| − | The ligands of DAF-12 various isomers of dafachronic acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450 enzime. | + | The ligands of DAF-12 are various isomers of dafachronic acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450 enzime. |
===Physiological effects of DAF-12=== | ===Physiological effects of DAF-12=== | ||
Latest revision as of 01:44, 26 October 2010
This experience page is provided so that any user may enter their experience using this part.
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how you used this part and how it worked out.
Ligand
The ligands of DAF-12 are various isomers of dafachronic acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450 enzime.
Physiological effects of DAF-12
daf-12 in Caenorhabditis elegans plays a key role in the regulation of development and determination of adult longevity. It has effects also on resistance to oxidative and thermal stress which makes daf-12 the first gene with alleles that can extend or shorten lifespan.
Possible applications of GAL4-DAF-12
By the addition of lipid ligands (dafachronic acids), the created system activates the expression of any kind of genes fused to UAS(upstream activation seqence)previously. Also can be used as a lipid sensor by activating reporter genes (e.g. Luciferase).
Applications of BBa_K364328
User Reviews
UNIQ2aeca2a084063c67-partinfo-00000000-QINU UNIQ2aeca2a084063c67-partinfo-00000001-QINU