Difference between revisions of "Part:BBa K364320:Experience"

(Applications of BBa_K364320)
(Possible applications of GAL4-NHR-8)
Line 12: Line 12:
  
 
===Possible applications of GAL4-NHR-8===
 
===Possible applications of GAL4-NHR-8===
By the addition of lipid ligands(unknown), the created system activates the expression of any kind of genes fused to UAS(upstream activation seqence)previously.
+
By the addition of lipid ligands(unknown), the created system activates the expression of any kind of genes fused to UAS(upstream activation seqence)previously. Also can be used as a lipid sensor by activating reporter genes (e.g. Luciferase).
  
 
===Applications of BBa_K364320===
 
===Applications of BBa_K364320===

Revision as of 22:48, 25 October 2010


Picture of gel electrophoresis: Gal4-NHR8 in pCDNA3.1 resulting an insert of 953 bp.

Physiological effects of NHR-8

NHR-8 is required for gut function and may respond to the food signal.

The nhr-8 gene mutants have abnormally low resistance to the toxins colchicine and chloroquine.This resembles the regulation of protective metabolic enzymes by xenobiotic-sensing nuclear receptors.

NHR-8 may thus mediate a subset of the resistance traits promoted by PGP-3.

Possible applications of GAL4-NHR-8

By the addition of lipid ligands(unknown), the created system activates the expression of any kind of genes fused to UAS(upstream activation seqence)previously. Also can be used as a lipid sensor by activating reporter genes (e.g. Luciferase).

Applications of BBa_K364320

User Reviews

UNIQdc81fae91089da89-partinfo-00000000-QINU UNIQdc81fae91089da89-partinfo-00000001-QINU