Difference between revisions of "Part:BBa K364307"

Revision as of 20:17, 25 October 2010

Human ER DBD

Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol[1] (estrogen) , which is a member of the nuclear hormone family of intracellular receptors. The main function of the estrogen receptor is as a DNA-binding transcription factor that regulates gene expression.

More on ER here: [http://en.wikipedia.org/wiki/RXRA].

ER Uniprot: [http://www.uniprot.org/uniprot/P03372].

View the ER DBD crystal structure here: [http://www.pdb.org/pdb/explore/jmol.do?structureId=1HCQ&bionumber=1].

Description of the RXRa DBD crystal structure with reference here: [http://www.cell.com/retrieve/pii/009286749390390C].

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 4: / Line 4: @@
 Estrogen receptor refers to a group of receptors that are activated by the hormone 17&#946;-estradiol[1] (estrogen) , which is a member of the nuclear hormone family of intracellular receptors.
 The main function of the estrogen receptor is as a DNA-binding transcription factor that regulates gene expression.
+More on ER here: [http://en.wikipedia.org/wiki/RXRA].
+ER Uniprot: [http://www.uniprot.org/uniprot/P03372].
+View the ER DBD crystal structure here: [http://www.pdb.org/pdb/explore/jmol.do?structureId=1HCQ&bionumber=1].
 [[Image:ER-DBD.jpg|800px|thumb|center|]]
+Description of the RXRa DBD crystal structure with reference here: [http://www.cell.com/retrieve/pii/009286749390390C].