Difference between revisions of "Part:BBa K364202"
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Coding sequence of Bax (Bcl-2-associated X) protein which is a pro-apoptotic member of the Bcl-2 protein family. It contains three BH (Bcl-2 homology) domains, can form homo- and heterodimers and plays essential role in the formation of MOMP (Mitochondrial outer membrane permeabilization) leading to apoptosis which is the most frequent type of PCD (Programmed cell death). | Coding sequence of Bax (Bcl-2-associated X) protein which is a pro-apoptotic member of the Bcl-2 protein family. It contains three BH (Bcl-2 homology) domains, can form homo- and heterodimers and plays essential role in the formation of MOMP (Mitochondrial outer membrane permeabilization) leading to apoptosis which is the most frequent type of PCD (Programmed cell death). | ||
| − | [[Image:Team_Debrecen_20101008.jpg|800px|thumb|center]] | + | [[Image:Team_Debrecen_20101008.jpg|800px|thumb|center|Picture of gel electrophoresis: hBAX in pSB1C3 resulting an insert of 573 bp. Circular pSB1C3-hBAX and restricted PMAT-hBAX can be seen as control on the gel.]] |
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Revision as of 13:40, 23 October 2010
hBAX
Coding sequence of Bax (Bcl-2-associated X) protein which is a pro-apoptotic member of the Bcl-2 protein family. It contains three BH (Bcl-2 homology) domains, can form homo- and heterodimers and plays essential role in the formation of MOMP (Mitochondrial outer membrane permeabilization) leading to apoptosis which is the most frequent type of PCD (Programmed cell death).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 449
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]