Difference between revisions of "Part:BBa K346088"

Revision as of 01:43, 23 October 2010

RBS(BBa_B0034)+MerC

This part is constructed for the expression of merC. MerC can transport Hg(II) into the cytosol without the help of merP. For a long time, merC is considered to be of no use in the resistance to Hg(II) because mutations that affect the expression of MerC did not affect the resistance. The discovery in Thipobacillus isolated from mercury mines of operons that apparently had only merC and no merT genes forced reconsideration of the view that merC is vestigal. It has been proposed that merC may be needed under conditions of very high Hg (II) exprosure, perhaps because merC system can uptake (Hg (II) without the need of merP.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 384
1000
COMPATIBLE WITH RFC[1000]

@@ Line 1: / Line 1: @@
 __NOTOC__
 <partinfo>BBa_K346088 short</partinfo>
 This part is constructed for the expression of merC. MerC can transport Hg(II) into the cytosol without the help of merP.
+For a long time, merC is considered to be of no use in the resistance to Hg(II) because mutations that affect the expression of MerC did not affect the resistance. The discovery in Thipobacillus isolated from mercury mines of operons that apparently had only merC and no merT genes forced reconsideration of the view that merC is vestigal.
+It has been proposed that merC may be needed under conditions of very high Hg (II) exprosure, perhaps because merC system can uptake (Hg (II) without the need of merP.
 <!-- Add more about the biology of this part here