Difference between revisions of "Part:BBa K364303"
Line 2: Line 2:
 
<partinfo>BBa_K364303 short</partinfo>
 
<partinfo>BBa_K364303 short</partinfo>
  
−
Caenorhabditis elegans nuclear receptor.
+
The nuclear hormone receptor DAF-12 from Caenorhabditis elegans is activated by dafachronic
 +
acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450. DAF-12 activation
 +
is a critical checkpoint in C. elegans for acquisition of reproductive competence and for entry into
 +
adulthood rather than dauer diapause.
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here
Line 16: Line 19:
 
<partinfo>BBa_K364303 parameters</partinfo>
 
<partinfo>BBa_K364303 parameters</partinfo>
 
<!-- -->
 
<!-- -->
−
 
−
The nuclear hormone receptor DAF-12 from Caenorhabditis elegans is activated by dafachronic
 
−
acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450. DAF-12 activation
 
−
is a critical checkpoint in C. elegans for acquisition of reproductive competence and for entry into
 
−
adulthood rather than dauer diapause.
 

Revision as of 11:52, 24 October 2010

DAF-12 LBD

The nuclear hormone receptor DAF-12 from Caenorhabditis elegans is activated by dafachronic acids, which derive from sterols upon oxidation by DAF-9, a cytochrome P450. DAF-12 activation is a critical checkpoint in C. elegans for acquisition of reproductive competence and for entry into adulthood rather than dauer diapause.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]