Difference between revisions of "Part:BBa K5115071"
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===Introduction=== | ===Introduction=== | ||
| − | ''NixA'' is a high-affinity nickel transporter in ''elicobacter pylori''. It | + | ''NixA'' is a high-affinity nickel transporter in ''elicobacter pylori''. It belongs to the NiCoT family of transporters and facilitates the import of Ni²⁺ ions across the bacterial cytoplasmic membrane. These nickel ions make up the active sites of urease and hydrogenase, enzymes crucial for ''H. pylori'''s ability to survive in the highly acidic environment of the stomach.<ref>Fischer, F., Robbe-Saule, M., Turlin, E., Mancuso, F., Michel, V., Richaud, P., Veyrier, F. J., Reuse, H. D., & Vinella, D. (2016). Characterization in Helicobacter pylori of a Nickel Transporter Essential for Colonization That Was Acquired during Evolution by Gastric Helicobacter Species. PLOS Pathogens, 12(12), e1006018.</ref> |
===Usage and Biology=== | ===Usage and Biology=== | ||
Revision as of 02:30, 28 September 2024
NixA, without stop codon
Introduction
NixA is a high-affinity nickel transporter in elicobacter pylori. It belongs to the NiCoT family of transporters and facilitates the import of Ni²⁺ ions across the bacterial cytoplasmic membrane. These nickel ions make up the active sites of urease and hydrogenase, enzymes crucial for H. pylori's ability to survive in the highly acidic environment of the stomach.[1]
Usage and Biology
Characterization
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
References
- ↑ Fischer, F., Robbe-Saule, M., Turlin, E., Mancuso, F., Michel, V., Richaud, P., Veyrier, F. J., Reuse, H. D., & Vinella, D. (2016). Characterization in Helicobacter pylori of a Nickel Transporter Essential for Colonization That Was Acquired during Evolution by Gastric Helicobacter Species. PLOS Pathogens, 12(12), e1006018.