Difference between revisions of "Part:BBa K4960030"
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===Usage and Biology=== | ===Usage and Biology=== | ||
Mutant Pvc13-E01-DARPin fused with the DARPin E01 structural domain can enhance the binding ability of PVCs to cells, ultimately enabling targeted delivery of target proteins.[1] | Mutant Pvc13-E01-DARPin fused with the DARPin E01 structural domain can enhance the binding ability of PVCs to cells, ultimately enabling targeted delivery of target proteins.[1] | ||
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Latest revision as of 14:29, 11 October 2023
pvc13_NTD-2*GGGSG-E01 DARPin-2*GGGSG -pvc13_CTD
A structural domain that can specifically recognize the EGFR receptor.
Profile
Name: pvc13_NTD-2*GGGSG-E01 DARPin-2*GGGSG -pvc13_CTD
Base Pairs: 1824bp
Origin: Synthetic
Properties: A structural domain that can specifically recognize the EGFR receptor.
Usage and Biology
Mutant Pvc13-E01-DARPin fused with the DARPin E01 structural domain can enhance the binding ability of PVCs to cells, ultimately enabling targeted delivery of target proteins.[1]
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 309
Illegal BglII site found at 1674 - 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
References
[1]Kreitz J, Friedrich MJ, Guru A, Lash B, Saito M, Macrae RK, Zhang F. Programmable protein delivery with a bacterial contractile injection system. Nature. 2023 Apr;616(7956):357-364. doi: 10.1038/s41586-023-05870-7. Epub 2023 Mar 29.