Difference between revisions of "Part:BBa K4825013"
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The terminal enzyme in the mitochondrial respiratory chain is COX. COX contains 13 mitochondrial and nuclear encoded subunits. The nuclear encoded subunits have yet unknown function but are hypothesized to play a role in constructing and regulating the complex. The mitochondrial encoded subunits aids in the performance of the ETC and proton pumping activities. The N- terminal localization signals from COXIV is used to target Leu4p to mitochondria, and the first 26 amino acids from COX4 appends to the N-terminus of the corresponding open reading frame. | The terminal enzyme in the mitochondrial respiratory chain is COX. COX contains 13 mitochondrial and nuclear encoded subunits. The nuclear encoded subunits have yet unknown function but are hypothesized to play a role in constructing and regulating the complex. The mitochondrial encoded subunits aids in the performance of the ETC and proton pumping activities. The N- terminal localization signals from COXIV is used to target Leu4p to mitochondria, and the first 26 amino acids from COX4 appends to the N-terminus of the corresponding open reading frame. | ||
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===Usage and Biology=== | ===Usage and Biology=== | ||
| + | The gene encodes the subunit IV isoform 1 which is a nuclear encoded subunit in the human mitochondrial respiratory chain located at the 3’ of the NOC4 gene. | ||
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Latest revision as of 18:49, 11 October 2023
COX4
The terminal enzyme in the mitochondrial respiratory chain is COX. COX contains 13 mitochondrial and nuclear encoded subunits. The nuclear encoded subunits have yet unknown function but are hypothesized to play a role in constructing and regulating the complex. The mitochondrial encoded subunits aids in the performance of the ETC and proton pumping activities. The N- terminal localization signals from COXIV is used to target Leu4p to mitochondria, and the first 26 amino acids from COX4 appends to the N-terminus of the corresponding open reading frame.
Usage and Biology
The gene encodes the subunit IV isoform 1 which is a nuclear encoded subunit in the human mitochondrial respiratory chain located at the 3’ of the NOC4 gene.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal XbaI site found at 61
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23INCOMPATIBLE WITH RFC[23]Illegal XbaI site found at 61
- 25INCOMPATIBLE WITH RFC[25]Illegal XbaI site found at 61
- 1000COMPATIBLE WITH RFC[1000]