Difference between revisions of "Part:BBa K4830008:Design"
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__NOTOC__ | __NOTOC__ | ||
− | <partinfo> | + | <partinfo>BBa_K4830009 short</partinfo> |
− | <partinfo> | + | <partinfo>BBa_K4830009 SequenceAndFeatures</partinfo> |
===Design Notes=== | ===Design Notes=== | ||
− | The design of | + | The design of ngRNA includes the U6 promoter, spacer, guide RNA scaffold, and polyA tail. The unique ngRNA was designed based on SNP data. |
===Source=== | ===Source=== | ||
− | + | ||
+ | SNPs were retrieved from the paper cited in References. | ||
===References=== | ===References=== | ||
+ | Gharahkhani, P. et al. (2021) ‘Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries’, Nature Communications, 12(1). doi:10.1038/s41467-020-20851-4. |
Revision as of 20:53, 11 October 2023
POAG snp1-3 ngRNA
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The design of ngRNA includes the U6 promoter, spacer, guide RNA scaffold, and polyA tail. The unique ngRNA was designed based on SNP data.
Source
SNPs were retrieved from the paper cited in References.
References
Gharahkhani, P. et al. (2021) ‘Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries’, Nature Communications, 12(1). doi:10.1038/s41467-020-20851-4.