Difference between revisions of "Part:BBa K4656001"

Revision as of 15:15, 11 September 2023

TDC

Tdc can remove the carboxyl group from 5-hydroxytryptophan (5-HTP) and convert it into serotonin (5-hydroxytryptophan, 5-HT). Tryptophan decarboxylase exists widely in animals and plants, especially in the central nervous system and gastrointestinal tract. 5-HTP is a precursor substance of neurotransmitter 5-HT, which is an important neurotransmitter, serving as intestinal motor in terms of intestinal physiological function, and plays a vital role in alleviating chronic constipation.

The synthesis of 5-HT

Usage and Biology

In our project, tdc and tph together catalyze the generation of 5-HT, when sensing a decrease in butyrate concentration.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BglII site found at 1248
Illegal BamHI site found at 732
Illegal BamHI site found at 834
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 340
Illegal NgoMIV site found at 775
Illegal NgoMIV site found at 1330
Illegal AgeI site found at 478
Illegal AgeI site found at 1402
1000
COMPATIBLE WITH RFC[1000]

@@ Line 10: / Line 10: @@
 ===Usage and Biology===
 In our project, tdc and tph together catalyze the generation of 5-HT, when sensing a decrease in butyrate concentration.
-<html><BR><BR><center><img style="display: block;-webkit-user-select: none;margin: auto;cursor: zoom-in;background-color: hsl(0,0%,90%);transition: background-color 300ms;" src="https://static.igem.wiki/teams/4656/wiki/part-plam-tph-tdc.jpg" width="400" height="200"></center></html>
+<html><BR><BR><center><img style="display: block;-webkit-user-select: none;margin: auto;cursor: zoom-in;background-color: hsl(0,0%,90%);transition: background-color 300ms;" src="https://static.igem.wiki/teams/4656/wiki/part-plam-tph-tdc.jpg" width="600" height="300"></center></html>
 ===Sequence and Features===