Difference between revisions of "Part:BBa K4129102:Design"

Latest revision as of 15:18, 12 October 2022

The fungal synthetic transcription factor, FunsTF04 (LexA-LL-Hmox1-B112-SV40)

Design Notes

FunsTF04 consists of modules from LexA, Hmox1 and B112, and these modules can individually be exchanged with other domains. The exchange of modules follow a standardised USER assembly.

Source

FunsTF04 was de novo synthesised as a gene block from IDT

References

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Erill I, Escribano M, Campoy S, Barbé J. In silico analysis reveals substantial variability in the gene contents of the gamma proteobacteria LexA-regulon. Bioinformatics. 2003 Nov 22;19(17):2225-36. doi: 10.1093/bioinformatics/btg303. PMID: 14630651.

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Ottoz DS, Rudolf F, Stelling J. Inducible, tightly regulated and growth condition-independent transcription factor in Saccharomyces cerevisiae. Nucleic Acids Res. 2014;42(17):e130. doi: 10.1093/nar/gku616. Epub 2014 Jul 17. PMID: 25034689; PMCID: PMC4176152.

Radman M. SOS repair hypothesis: phenomenology of an inducible DNA repair which is accompanied by mutagenesis. Basic Life Sci. 1975;5A:355-67. doi: 10.1007/978-1-4684-2895-7_48. PMID: 1103845.