Difference between revisions of "Part:BBa K4241793"

 
 
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<partinfo>BBa_K4241793 short</partinfo>
 
<partinfo>BBa_K4241793 short</partinfo>
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<partinfo>BBa_K4241793 SequenceAndFeatures</partinfo>
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===Overview===
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Cecropin B isoform Q53 is an enhanced Cecropin B that shows increased antimicrobial ability against bacteria such as P. aeruginosa. This part is derived from the following publication: https://pubmed.ncbi.nlm.nih.gov/31045339/
  
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Cecropin B isoform Q53 is an enhanced Cecropin B that shows increased antimicrobial ability against bacteria such as P. aeruginosa.
 
  
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<!-- Add more about the biology of this part here
 
 
===Usage and Biology===
 
===Usage and Biology===
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Cecropin B Q53 is a naturally produced antimicrobial peptide isolated from Bombyx mori, this isoform differs from the other isoform E53 by replacing a single peptide; glutamic acid by glutamine. This peptide demonstrates strong antimicrobial properties against gram-negative and gram-positive bacteria. Furthermore, this peptide demonstrates high stability to pH and temperature variations as well as tolerance to high-salt concentration and low-toxicity to human cells.
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===References===
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Romoli, O., Mukherjee, S., Mohid, S. A., Dutta, A., Montali, A., Franzolin, E., Brady, D., Zito, F., Bergantino, E., Rampazzo, C., Tettamanti, G., Bhunia, A., &amp; Sandrelli, F. (2019). Enhanced silkworm cecropin B antimicrobial activity against pseudomonas aeruginosa from single amino acid variation. ACS Infectious Diseases, 5(7), 1200–1213. https://doi.org/10.1021/acsinfecdis.9b00042
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<span class='h3bb'>Sequence and Features</span>
 
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<partinfo>BBa_K4241793 SequenceAndFeatures</partinfo>
 
  
  

Latest revision as of 10:13, 10 October 2022


Cecropin B Q53


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 77
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Overview

Cecropin B isoform Q53 is an enhanced Cecropin B that shows increased antimicrobial ability against bacteria such as P. aeruginosa. This part is derived from the following publication: https://pubmed.ncbi.nlm.nih.gov/31045339/


Usage and Biology

Cecropin B Q53 is a naturally produced antimicrobial peptide isolated from Bombyx mori, this isoform differs from the other isoform E53 by replacing a single peptide; glutamic acid by glutamine. This peptide demonstrates strong antimicrobial properties against gram-negative and gram-positive bacteria. Furthermore, this peptide demonstrates high stability to pH and temperature variations as well as tolerance to high-salt concentration and low-toxicity to human cells.

References

Romoli, O., Mukherjee, S., Mohid, S. A., Dutta, A., Montali, A., Franzolin, E., Brady, D., Zito, F., Bergantino, E., Rampazzo, C., Tettamanti, G., Bhunia, A., & Sandrelli, F. (2019). Enhanced silkworm cecropin B antimicrobial activity against pseudomonas aeruginosa from single amino acid variation. ACS Infectious Diseases, 5(7), 1200–1213. https://doi.org/10.1021/acsinfecdis.9b00042