Difference between revisions of "Part:BBa K4165225"

 
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Clamp [10] composed of Tau Binding Peptide WWW (BBa_K4165007) , linker length of GGSGGG (BBa_K4165224), Tau Binding Peptide TD28rev  (BBa_K4165006). Our Clamp design was based on our project aim for binding with Tau and amyloid beta for further degradation.
 
Clamp [10] composed of Tau Binding Peptide WWW (BBa_K4165007) , linker length of GGSGGG (BBa_K4165224), Tau Binding Peptide TD28rev  (BBa_K4165006). Our Clamp design was based on our project aim for binding with Tau and amyloid beta for further degradation.
  
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===Usage and Biology===
 
===Usage and Biology===
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Clamp [10] composed of Tau Binding Peptide WWW ( BBa_K4165007) , linker length of GGSGGGGG, Tau Binding Peptide TD28rev  (BBa_K4165006). Our Clamp design was based on our project aim for binding with Tau and amyloid beta for further degradation.
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===3D Modeling and Ranking===
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TRRosetta models this composite part with a score of 5 out of 6 according to our quality assessment code (you can find the python script file on the programming club page with further explanation of how you can optimize it to your needs).
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<html>
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<p><img src="https://static.igem.wiki/teams/4165/wiki/parts-registry/10.png" style="margin-left:200px;" alt="" width="500" /></p>
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</html>
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                            Figure 1. The 3D structure of Clamp 10 modeled by TRrosetta
  
 
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Revision as of 07:51, 8 October 2022


Clamp [10]

Clamp [10] composed of Tau Binding Peptide WWW (BBa_K4165007) , linker length of GGSGGG (BBa_K4165224), Tau Binding Peptide TD28rev (BBa_K4165006). Our Clamp design was based on our project aim for binding with Tau and amyloid beta for further degradation.


Usage and Biology

Clamp [10] composed of Tau Binding Peptide WWW ( BBa_K4165007) , linker length of GGSGGGGG, Tau Binding Peptide TD28rev (BBa_K4165006). Our Clamp design was based on our project aim for binding with Tau and amyloid beta for further degradation.

3D Modeling and Ranking

TRRosetta models this composite part with a score of 5 out of 6 according to our quality assessment code (you can find the python script file on the programming club page with further explanation of how you can optimize it to your needs). 

                            Figure 1. The 3D structure of Clamp 10 modeled by TRrosetta

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]