Difference between revisions of "Part:BBa K4165133"
Salma Sobhy (Talk | contribs) |
Omnia Alaa11 (Talk | contribs) |
||
Line 6: | Line 6: | ||
===Usage and Biology=== | ===Usage and Biology=== | ||
− | Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC50 of 74 ± 4 and | + | Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC50 of 74 ± 4 and ΔG of 3700. |
<!-- --> | <!-- --> |
Revision as of 17:36, 11 October 2022
HTRA Binding Peptide 39
part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein
Usage and Biology
Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC50 of 74 ± 4 and ΔG of 3700.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
References
Beuming, T., Farid, R., & Sherman, W. (2009). High‐energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Science, 18(8), 1609-1619.