Difference between revisions of "Part:BBa K4165140"
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part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein | part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein | ||
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===Usage and Biology=== | ===Usage and Biology=== | ||
| + | Synthetic peptide acquired by Phage display, Binds specifically to PDZ domain of HTRA1 and HTRA3 Proteins with G of –8.0 and IC50 of 2.8 ± 0.3 | ||
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<partinfo>BBa_K4165140 SequenceAndFeatures</partinfo> | <partinfo>BBa_K4165140 SequenceAndFeatures</partinfo> | ||
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===Functional Parameters=== | ===Functional Parameters=== | ||
| + | Got score of 5 out of 6 in our Quality assessment code after modeling by AlphaFold2.0 | ||
| + | cbeta_deviations = 0, clashscore = 0, molprobity = 1.24, ramachandran_favored = 80, ramachandran_outliers = 20, Qmean_4 = -1.332902, Qmean6 = -0.484265 | ||
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| + | ===Modeling=== | ||
| + | <html> | ||
| + | <p><img src="https://static.igem.wiki/teams/4165/wiki/parts-registry/htra1-bp/h1e.jpg" style="margin-left:200px;" alt="" width="500" /></p> | ||
| + | </html> | ||
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| + | Figure 1.: 3D Model of H1E peptide Modelled by AlphaFold2.0 displayed in Pyomol | ||
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<partinfo>BBa_K4165140 parameters</partinfo> | <partinfo>BBa_K4165140 parameters</partinfo> | ||
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Revision as of 20:07, 6 October 2022
Status: 500
Content-type: text/html
Software error:
syntax error at /websites/parts.igem.org/cgi/lib/Range.pm line 230, near ""<BR>$group_name, $year, $team_name, $team_digits, $range_name, $range_prefix")" Compilation failed in require at /websites/parts.igem.org/cgi/lib/Part.pm line 16. BEGIN failed--compilation aborted at /websites/parts.igem.org/cgi/lib/Part.pm line 16. Compilation failed in require at /websites/parts.igem.org/cgi/partsdb/putout.cgi line 8. BEGIN failed--compilation aborted at /websites/parts.igem.org/cgi/partsdb/putout.cgi line 8.
For help, please send mail to this site's webmaster, giving this error message and the time and date of the error.
part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein
Usage and Biology
Synthetic peptide acquired by Phage display, Binds specifically to PDZ domain of HTRA1 and HTRA3 Proteins with G of –8.0 and IC50 of 2.8 ± 0.3
Sequence and Features
Status: 500 Content-type: text/html
Software error:
syntax error at /websites/parts.igem.org/cgi/lib/Range.pm line 230, near ""<BR>$group_name, $year, $team_name, $team_digits, $range_name, $range_prefix")" Compilation failed in require at /websites/parts.igem.org/cgi/lib/Part.pm line 16. BEGIN failed--compilation aborted at /websites/parts.igem.org/cgi/lib/Part.pm line 16. Compilation failed in require at /websites/parts.igem.org/cgi/partsdb/putout.cgi line 8. BEGIN failed--compilation aborted at /websites/parts.igem.org/cgi/partsdb/putout.cgi line 8.
For help, please send mail to this site's webmaster, giving this error message and the time and date of the error.
Functional Parameters
Got score of 5 out of 6 in our Quality assessment code after modeling by AlphaFold2.0 cbeta_deviations = 0, clashscore = 0, molprobity = 1.24, ramachandran_favored = 80, ramachandran_outliers = 20, Qmean_4 = -1.332902, Qmean6 = -0.484265
Modeling
Figure 1.: 3D Model of H1E peptide Modelled by AlphaFold2.0 displayed in Pyomol
Status: 500 Content-type: text/html
Software error:
syntax error at /websites/parts.igem.org/cgi/lib/Range.pm line 230, near ""<BR>$group_name, $year, $team_name, $team_digits, $range_name, $range_prefix")" Compilation failed in require at /websites/parts.igem.org/cgi/lib/Part.pm line 16. BEGIN failed--compilation aborted at /websites/parts.igem.org/cgi/lib/Part.pm line 16. Compilation failed in require at /websites/parts.igem.org/cgi/partsdb/putout.cgi line 8. BEGIN failed--compilation aborted at /websites/parts.igem.org/cgi/partsdb/putout.cgi line 8.
For help, please send mail to this site's webmaster, giving this error message and the time and date of the error.