Difference between revisions of "Part:BBa K4165139"
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                             Figure 1.: Predicted 3D structure of Synthetic peptide TLKIVW.
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                             Figure 1: Predicted 3D structure of Synthetic peptide TLKIVW.
  
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modeled by alphafold2 and apptest.
 
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best model obtained from apptest
 
  
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<p style=" font-weight: bold; font-size:13px;"> Table 1: Quality assessment parameters of TLKIVW model. </p>
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Table 1.: Quality assessment parameters of TLKIVW model.
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Revision as of 16:49, 5 October 2022


TLKIVW Peptide

Tau binding peptide targeting the PHF seed of Tau

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Dry Lab

Modeling

TLKIVW were modeled by AlphaFold2 and Apptest. The best model obtained from Apptest 


                            Figure 1: Predicted 3D structure of Synthetic peptide TLKIVW.


Table 1: Quality assessment parameters of TLKIVW model.


References

1.Sievers, S. A., Karanicolas, J., Chang, H. W., Zhao, A., Jiang, L., Zirafi, O., ... & Eisenberg, D. (2011). Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature, 475(7354), 96-100.