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[[File:Aerolysin toxicity.png|800px|center|Aerolysin toxicity]]
 
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'''Figure 1. The toxicity of Aerolysin to <i>Dreissena bugensis</i>.'''
  
 
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Revision as of 04:36, 7 October 2022


Coding sequence for Aerolysin

Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and host cell death. The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter. This part has been codon optimized for expression in Escherichia coli.

Aerolysin toxicity

Figure 1. The toxicity of Aerolysin to Dreissena bugensis.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 206
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 75
    Illegal AgeI site found at 313
    Illegal AgeI site found at 1270
  • 1000
    COMPATIBLE WITH RFC[1000]