Difference between revisions of "Part:BBa K4390009"

Revision as of 17:04, 3 October 2022

Mytilus edulis Metallothionein

Metallothionein (MT) is a small protein (around 6-7 kDa) which is rich in cysteine. These thiol group in cysteines provide ability to chelate almost all heavy metal ions including Cd2+, Hg2+, Pb2+ and As3+, but had been shown that has higher binding affinity with Zn2+ (). The ability of chelating heavy metals provides the metal tolerance for its hosts. For its ability to binding heavy metal strongly, this part can be used to build structure which can capture heavy metal ions in aqueous environment. This MT sequence was obtained from Mytilus edulis as a species which originally lived in aqueous environment, and designed as a C part for JUMP assembly.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K4390009 short</partinfo>
-Metallothionein from Mytilus edulis. This part was designed as a JUMP C part. Metallothioneins chelate heavy metal ions, including Cd2+, Hg2+, Pb2+, As3+ and Zn2+.
+Metallothionein (MT) is a small protein (around 6-7 kDa) which is rich in cysteine. These thiol group in cysteines provide ability to chelate almost all heavy metal ions including Cd2+, Hg2+, Pb2+ and As3+, but had been shown that has higher binding affinity with Zn2+ (). The ability of chelating heavy metals provides the metal tolerance for its hosts.
+For its ability to binding heavy metal strongly, this part can be used to build structure which can capture heavy metal ions in aqueous environment. This MT sequence was obtained from Mytilus edulis as a species which originally lived in aqueous environment, and designed as a C part for JUMP assembly.
 <!-- Add more about the biology of this part here