Difference between revisions of "Part:BBa K3733042"
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PhoA, a signal peptide of Sec pathway in <i>Escherichia coli</i>, have the capability to guide the LL-37 excrete out of the cell.
 
PhoA, a signal peptide of Sec pathway in <i>Escherichia coli</i>, have the capability to guide the LL-37 excrete out of the cell.
 
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<span class='h3bb'>Sequence and Features</span>
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<partinfo>BBa_K3733042 SequenceAndFeatures</partinfo>
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===Reference===
 
===Reference===
 
Huang F, Qianhui S, Zhaojie Q, et al. Anticancer actions of azurin and its derived peptide p28[J]. The protein journal, 2020, 39(2): 182-189.
 
Huang F, Qianhui S, Zhaojie Q, et al. Anticancer actions of azurin and its derived peptide p28[J]. The protein journal, 2020, 39(2): 182-189.

Revision as of 15:39, 20 October 2021

PhoA-azurin with a His-tag

Azurin is a copper-containing redox protein secreted by Pseudomonas aeruginosa. Azurin preferentially enters a variety of cancer cells and induces apoptosis or cell cycle arrest, thereby playing an anti-cancer effect. A 6×His tag was added in order to purify the protein. PhoA, a signal peptide of Sec pathway in Escherichia coli, have the capability to guide the LL-37 excrete out of the cell.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Reference

Huang F, Qianhui S, Zhaojie Q, et al. Anticancer actions of azurin and its derived peptide p28[J]. The protein journal, 2020, 39(2): 182-189.