Difference between revisions of "Part:BBa K3740009"
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===Description=== | ===Description=== | ||
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===Sequence and Features=== | ===Sequence and Features=== | ||
<partinfo>BBa_K3740009 SequenceAndFeatures</partinfo> | <partinfo>BBa_K3740009 SequenceAndFeatures</partinfo> | ||
Latest revision as of 12:12, 18 October 2021
Holin S
Description
Lysis of the engineered bacteria.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
2021 SZPT-China
Biology
The S gene of lambda bacteriophage has the characteristics of a double initiation motif, which can encode two proteins with opposite functions, S107 and S105. Among them, S105 plays the function of holin. It accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space.
References
[1] Yibo S, Jianhe S, Shi Y, et al. Current advance in the topological structure and function of holin encoded by bacteriophage lambda[J]. Acta Microbiologica Sinica, 2012, 52(2):141-145