Difference between revisions of "Part:BBa K3962350"

Revision as of 18:25, 21 October 2021

HOK - Toxin in Hok/Sok

HOK is the toxin of the HOK/SOK toxin-antitoxin system. The HOK/SOKis a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The SOK transcript can bind to a homologous region on HOK mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived HOK toxin from the parent cell. Due to the short half-life of the SOK antitoxin, daughter cells inherit only small amounts and it is quickly degraded.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K3962350 short</partinfo>
-Sok is the antitoxin of the Hok/Sok toxin-antitoxin system. The Hok/Sok is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The Sok transcript can bind to a homologous region onHok mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived Hok toxin from the parent cell. Due to the short half-life of the Sok antitoxin, daughter cells inherit only small amounts and it is quickly degraded.
+HOK is the toxin of the HOK/SOK toxin-antitoxin system. The HOK/SOKis a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The SOK transcript can bind to a homologous region on HOK mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived HOK toxin from the parent cell. Due to the short half-life of the SOK antitoxin, daughter cells inherit only small amounts and it is quickly degraded.
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