Difference between revisions of "Part:BBa K3833002"

Latest revision as of 14:11, 21 October 2021

Integrin Binding Domain (GFPGER)

Integrins are transmembrane receptors that allow for cell adhesion to a cell's extracellular matrix. Integrin recognition sequences can form a basis for binding domains within proteins [1]. The documented part is meant for insertion into the triple helical structure of Scl2 (Part BBa_K3833000) in order to allow for cell adhesion to hydrogels containing the protein. This part contains the integrin binding domain GFPGER.

Sources:
[1] Seo, N., Russell, B. H., Rivera, J. J., Liang, X., Xu, X., Afshar-Kharghan, V., & Höök, M. (2010). An engineered α1 integrin-binding collagenous sequence. Journal of Biological Chemistry, 285(40), 31046-31054. Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K3833002 short</partinfo>
-x
+Integrins are transmembrane receptors that allow for cell adhesion to a cell's extracellular matrix. Integrin recognition sequences can form a basis for binding domains within proteins [1]. The documented part is meant for insertion into the triple helical structure of Scl2 (Part BBa_K3833000) in order to allow for cell adhesion to hydrogels containing the protein. This part contains the integrin binding domain GFPGER.
+<br>'''Sources:'''
+<br>[1] Seo, N., Russell, B. H., Rivera, J. J., Liang, X., Xu, X., Afshar-Kharghan, V., & Höök, M. (2010). An engineered α1 integrin-binding collagenous sequence. Journal of Biological Chemistry, 285(40), 31046-31054.
 <!-- Add more about the biology of this part here
 ===Usage and Biology===