Difference between revisions of "Part:BBa K4040007"
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Revision as of 00:34, 15 September 2021
CD8 Transmembrane Domain
The transmembrane domain of the CAR performs a signal transduction role after the interaction between the S protein of pseudo- SARS-CoV-2 and the CARs. In this part, we used the CD8 hinge and the CD8 transmembrane domain presented in the αCD19 CAR for T cell to construct the transmembrane domain of our CAR-macrophage.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 22
- 1000COMPATIBLE WITH RFC[1000]