Difference between revisions of "Part:BBa K3378888"
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===Usage and Biology=== | ===Usage and Biology=== | ||
| − | + | LRAP can self-assemble into a chain structure composed of nanospheres by relying on its C-terminal domain, and the presence of calcium ions can enhance its ability. Non-phosphorylated LRAP tends to induce the formation of ordered hydroxyapatite (HA), while phosphorylated LRAP tend to stabilize amorphous calcium phosphate (ACP) and prevent their conversion to hydroxyapatite in vitro. So the non-phosphorylation LRAP are sufficient to transform ACP into ordered bundles of apatite crystals.We also found that LRAP has the ability to bind to natural teeth. | |
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<span class='h3bb'>Sequence and Features</span> | <span class='h3bb'>Sequence and Features</span> | ||
Revision as of 16:38, 27 October 2020
LRAP(Leucine-rich Amelogenin Peptides)
Leucine-rich ameloblast peptide (LRAP) is an alternative splicing product expressed by ameloblast genes during enamel development. LRAP has N-terminal amino acids and C-terminal amino acids of whole amelogenin, so it has the similar characteristics to the total length of amelogenin.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 132
- 1000COMPATIBLE WITH RFC[1000]