Difference between revisions of "Part:BBa K3504007"
Line 10: Line 10:
 
==Improvements==
 
==Improvements==
 
This part was improved by changes in its sequence that allowed it to further protect the circuit.
 
This part was improved by changes in its sequence that allowed it to further protect the circuit.
−
[[Image:Gly-Ala2.png|thumb|right|Figure 1. Optimized Gly-Ala repeats.]]
+
[[Image:Gly-Ala2.PNG|thumb|right|Figure 1. Optimized Gly-Ala repeats.]]
 
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<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>
 
<partinfo>BBa_K3504007 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K3504007 SequenceAndFeatures</partinfo>

Revision as of 14:31, 20 October 2020


Gly-Ala repeats

Part Description

Glycine-Alanine repeat (GAr) sequence of the Epstein-Barr virus-encoded EBNA-1 prevents presentation of antigenic peptides to major histocompatibility complex class I molecules. This has been attributed to its capacity to suppress mRNA translation in cis.

Usage

Characterization

Improvements

This part was improved by changes in its sequence that allowed it to further protect the circuit.

Figure 1. Optimized Gly-Ala repeats.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 40
    Illegal NgoMIV site found at 64
    Illegal NgoMIV site found at 262
    Illegal NgoMIV site found at 403
    Illegal NgoMIV site found at 442
    Illegal NgoMIV site found at 505
    Illegal NgoMIV site found at 571
  • 1000
    COMPATIBLE WITH RFC[1000]