Difference between revisions of "Part:BBa K3098006"
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The part contains the coding sequence for the antimicrobial peptide PgD5, which shows the ability to inhibit the growth of some filamentous fungi. Some research about the peptide suggests that this kind of effect comes into being by disrupting the membrane structure of the cell. The expression of PgD5 in E.coli has been done in the research in order to get its purified solution, and a strong inhibition has been tested in experiment. For the reason above, we chose this special peptide in our project as a defender of the silk relics. | The part contains the coding sequence for the antimicrobial peptide PgD5, which shows the ability to inhibit the growth of some filamentous fungi. Some research about the peptide suggests that this kind of effect comes into being by disrupting the membrane structure of the cell. The expression of PgD5 in E.coli has been done in the research in order to get its purified solution, and a strong inhibition has been tested in experiment. For the reason above, we chose this special peptide in our project as a defender of the silk relics. | ||
| − | + | [[File:PgD5.png|thumb|400px|center|]] | |
The tertiary structure of PgD5 has been shown here. | The tertiary structure of PgD5 has been shown here. | ||
For more information about the antimicrobial peptide, you can take the paper we have read as a reference.<html><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502332/">Identification of defensin-encoding genes of Picea glauca: characterization of PgD5, a conserved spruce defensin with strong antifungal activity</a></html> | For more information about the antimicrobial peptide, you can take the paper we have read as a reference.<html><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502332/">Identification of defensin-encoding genes of Picea glauca: characterization of PgD5, a conserved spruce defensin with strong antifungal activity</a></html> | ||
Revision as of 11:50, 21 October 2019
PgD5
The part contains the coding sequence for the antimicrobial peptide PgD5, which shows the ability to inhibit the growth of some filamentous fungi. Some research about the peptide suggests that this kind of effect comes into being by disrupting the membrane structure of the cell. The expression of PgD5 in E.coli has been done in the research in order to get its purified solution, and a strong inhibition has been tested in experiment. For the reason above, we chose this special peptide in our project as a defender of the silk relics.
The tertiary structure of PgD5 has been shown here. For more information about the antimicrobial peptide, you can take the paper we have read as a reference.Identification of defensin-encoding genes of Picea glauca: characterization of PgD5, a conserved spruce defensin with strong antifungal activity
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 91
- 1000COMPATIBLE WITH RFC[1000]