Difference between revisions of "Part:BBa K2989005"
| Line 7: | Line 7: | ||
===Usage=== | ===Usage=== | ||
Ce-HBsAg-70 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-70 is expressed. Ce-HBsAg-70 can competingly inhibit miR-HBsAg-70 to allow transcription of HBsAg It, together with miR-HBsAg-70, helps to form a regulation system. | Ce-HBsAg-70 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-70 is expressed. Ce-HBsAg-70 can competingly inhibit miR-HBsAg-70 to allow transcription of HBsAg It, together with miR-HBsAg-70, helps to form a regulation system. | ||
| + | |||
| + | https://2019.igem.org/wiki/images/1/19/T--Nanjing_NFLS--Parts_BBa_K2989005.jpg | ||
<!-- --> | <!-- --> | ||
Revision as of 15:54, 19 October 2019
Ce-HBsAg-70
Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites. Ce-HBsAg-70 can competingly inhibit miR-HBsAg-70 to allow transcription of HBsAg. It, together with miR-HBsAg-70, helps to form a regulation system.
Usage
Ce-HBsAg-70 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-70 is expressed. Ce-HBsAg-70 can competingly inhibit miR-HBsAg-70 to allow transcription of HBsAg It, together with miR-HBsAg-70, helps to form a regulation system.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]