Difference between revisions of "Part:BBa K3117004"

 
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<partinfo>BBa_K3117004 short</partinfo>
 
<partinfo>BBa_K3117004 short</partinfo>
  
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The linker BBa_K3117000 consists of for repeats of four times Glycin and one time Serin.
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The linker BBa_K3117000 consists of for repeats of four times Glycin and one time Serine. (Gly4Ser)4 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells.
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It has the characteristic of being very flexible. It can be fused to different macromolecules and function as a stable, flexible connection.
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<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Revision as of 19:08, 16 October 2019


((Glycine)x4-Serine)x4 Linker

The linker BBa_K3117000 consists of for repeats of four times Glycin and one time Serine. (Gly4Ser)4 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]