Difference between revisions of "Part:BBa K3182009"

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<partinfo>BBa_K3182009 short</partinfo>
 
<partinfo>BBa_K3182009 short</partinfo>
  
Syntethic peptide from our model. This part was designed to be assembled with BBa_K3182010.
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This part is a de novo antimicrobial peptide. The antimicrobial peptide was generated by the Parseq model and the antimicrobial activity was predicted by the Parseq model. This part was designed to be assembled with BBa_K3182010.
  
  

Revision as of 13:52, 5 October 2019


Parseq-α

This part is a de novo antimicrobial peptide. The antimicrobial peptide was generated by the Parseq model and the antimicrobial activity was predicted by the Parseq model. This part was designed to be assembled with BBa_K3182010.


Figure 1. General mechanism of action when the antimicrobial agent is fused to BBa_K3182010 which contains the linker, thrombin site and cellulose binding domain. The cellulose binding domain enables the attachment of antimicrobial agents (such as antimicrobial peptide or enzyme) to the cellulose. This also inactivates the agents when they are expressed in its bacterial host. Later, when the bandage comes in contact with thrombin in the blood, the antimicrobial agents will be activated upon cleavage of its thrombin site.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]