Difference between revisions of "Part:BBa K2653005:Design"
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===Design Notes=== | ===Design Notes=== | ||
| − | + | This protein is able to bind and form the heterodimerization with proteins from the erbB family, which is highly involved in proliferation and metastasis of cancer cells, also implicated in chemotherapeutic resistance through multiple signaling pathways. It has been proved that the downregulation of erbB-3 slows down the process several cancers. | |
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===Source=== | ===Source=== | ||
Latest revision as of 03:49, 18 October 2018
erbB3
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
This protein is able to bind and form the heterodimerization with proteins from the erbB family, which is highly involved in proliferation and metastasis of cancer cells, also implicated in chemotherapeutic resistance through multiple signaling pathways. It has been proved that the downregulation of erbB-3 slows down the process several cancers.