Difference between revisions of "Part:BBa K2729011"
Line 3: | Line 3: | ||
<partinfo>BBa_K2729011 short</partinfo> | <partinfo>BBa_K2729011 short</partinfo> | ||
+ | ==Usage and Biology== | ||
Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. | Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. | ||
− | + | ==Characterization== | |
− | + | The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices. | |
− | + | ==Sequence and Features== | |
− | + | ||
<partinfo>BBa_K2729011 SequenceAndFeatures</partinfo> | <partinfo>BBa_K2729011 SequenceAndFeatures</partinfo> | ||
− | + | ==Reference== | |
− | + | - [https://pubs.acs.org/doi/10.1021/bi500724k Membranotropic regions of the dengue virus prM protein] | |
− | == | + | |
− | + | ||
− | + |
Revision as of 14:34, 16 October 2018
DENV2 ancC-prM-E (Dengue Virus Serotype II)
Usage and Biology
Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.
Characterization
The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 946
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1397
Illegal AgeI site found at 1108
Illegal AgeI site found at 1450 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 349