Difference between revisions of "Part:BBa K2638100"
| Line 3: | Line 3: | ||
<partinfo>BBa_K2638100 short</partinfo> | <partinfo>BBa_K2638100 short</partinfo> | ||
| − | AhpC scavenges hydrogen peroxide and organic hydroperoxides. Together with AhpF | + | AhpC scavenges hydrogen peroxide and organic hydroperoxides. Together with AhpF it forms the holoenzyme Ahp / AhpR which catalyzes the reduction of peroxides to alcohols and water respectively. Oxidized AhpC can be restored after reduction by AhpF. Therefore, it offers an alternative to catalases like KatE and KatG. However AhpC is saturated at relatively low concentrations (10^(-5) M). If Ahp works properly and no highly oxidative stress is present, Ahp is sufficient to keep hydrogen peroxide concentrations low enough to prevent the activation of the OxyR regulon. |
AhpC catalyzes the following reaction: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH. | AhpC catalyzes the following reaction: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH. | ||
Latest revision as of 02:33, 18 October 2018
alkyl hydroperoxide reductase, C22 subunit (ahpC)
AhpC scavenges hydrogen peroxide and organic hydroperoxides. Together with AhpF it forms the holoenzyme Ahp / AhpR which catalyzes the reduction of peroxides to alcohols and water respectively. Oxidized AhpC can be restored after reduction by AhpF. Therefore, it offers an alternative to catalases like KatE and KatG. However AhpC is saturated at relatively low concentrations (10^(-5) M). If Ahp works properly and no highly oxidative stress is present, Ahp is sufficient to keep hydrogen peroxide concentrations low enough to prevent the activation of the OxyR regulon. AhpC catalyzes the following reaction: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]