Difference between revisions of "Part:BBa I760005"

Revision as of 14:44, 26 October 2007

Cu-sensitive promoter

Promoter from the copper-sensitive CusR/CusS two component signal system. (E.Coli)

Sequence and Features

Assembly Compatibility:

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 <!-- Add more about the biology of this part here
 ===Usage and Biology===
-This nucleotide sequence is believed to be able to bind with phosphorylated CusR transcription factor in E.coli. CusR protein is phosphorylated by CusS transmembrane protein in a case of high extracellular concentration of copper ions. After phosphorylation CusR interacts with described DNA sequence activating the transcription of CusA, CusB, CusC and CusF genes, which are coding the proteins of copper metabolic system.
+This nucleotide sequence is believed to be able to bind with phosphorylated CusR transcription factor in E.coli. CusR protein is phosphorylated by CusS transmembrane protein in a case of high extracellular concentration of copper ions. After phosphorylation CusR interacts with described DNA sequence and activates the transcription of CusA, CusB, CusC and CusF genes coding the proteins of copper metabolic system.
+Was used by Saint-Petersburg Team for constructing a copper biosensor system.