Difference between revisions of "Part:BBa K2524000"
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<partinfo>BBa_K2524000 short</partinfo>
 
<partinfo>BBa_K2524000 short</partinfo>
 
This part is an improvement of [[Part:BBa_K732001]].
 
This part is an improvement of [[Part:BBa_K732001]].
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Human Chorionic Gonadotropin (hCG)  is the hormone made by chorionic cells in the fetal part of the placenta. The presence of hCG is detectable by immunologic means within days pf fertilization and forms the foundation of the common pregnancy tests. The HCG Beta-subunit has the epitopes that are detected by pregnancy tests,  when hCG is present a pregnancy test will produce a positive result. It can be used in scenarios when detecting the autocatalysis of an enzyme. When HCG is fused to the end of an enzyme that is immobilized in a solution, if autocatalysis took place the HCG will be released into the solution and produce a positive pregnancy test result.  
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Human Chorionic Gonadotropin (hCG)  is the hormone made by chorionic cells in the fetal part of the placenta where it stimulates the ovaries to synthesize important steroids for the maintenance of pregnancy. It is a member of the beta chain glycoprotein hormone family. The glycoproteins are heterodimers consisting of an alpha subunit and beta subunit. The beta subunit determines bio-specificity. Six genes encode the hCG beta subunit which are inverted on chromosome 19q13.3 and is boarding the luteinizing hormone beta subunit gene.
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===Usage and Biology===
 
===Usage and Biology===
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The presence of hCG is detectable by immunologic means within days of fertilization and forms the foundation of the common pregnancy tests. The hCG Beta-subunit has the epitopes that are detected by pregnancy tests, when hCG is present a pregnancy test will produce a positive result. It can be used in scenarios when detecting the autocatalysis of an enzyme. When hCG is fused to the end of an enzyme that is immobilized in a solution, if autocatalysis took place the hCG will be released into the solution and produce a positive pregnancy test result.
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<img src="https://static.igem.org/mediawiki/2017/c/cf/T--Georgia_State--horseshoebranfromaquarium.jpg"  alt="Horseshoe Crab in Aquarium" width="250" height="250" style="float:right;">
  
 
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Revision as of 22:08, 31 October 2017


Synthetic Human Chorionic Gonadotropin (HCG) Beta Subunit This part is an improvement of Part:BBa_K732001. Human Chorionic Gonadotropin (hCG) is the hormone made by chorionic cells in the fetal part of the placenta where it stimulates the ovaries to synthesize important steroids for the maintenance of pregnancy. It is a member of the beta chain glycoprotein hormone family. The glycoproteins are heterodimers consisting of an alpha subunit and beta subunit. The beta subunit determines bio-specificity. Six genes encode the hCG beta subunit which are inverted on chromosome 19q13.3 and is boarding the luteinizing hormone beta subunit gene.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]