Difference between revisions of "Part:BBa K2232001"

Revision as of 09:20, 28 October 2017

OF4-nhaC

This part is the coding sequence (CDS) of the Na+/H+ antiporter from The Bacillus pseudofirmus OF4 (GenBank Acc.No. CP001878).

Usage and Biology

The gene nhaC from the Bacillus pseudofirmus OF4 encodes the Na+/H+ antiporter, which regulates cytoplasmic pH value by coupling net H+ uptake with Na+ extrusion. NhaC, the first demonstrated alkaliphile Na+/H+ antiporter, as part of a complement of antiporters in the wild-type alkaliphile, apparently plays a role over a wide range of pH values.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 216
1000
COMPATIBLE WITH RFC[1000]

@@ Line 5: / Line 5: @@
 This part is the coding sequence (CDS) of the Na+/H+ antiporter from The Bacillus pseudofirmus OF4 (GenBank Acc.No. CP001878).
-<!-- ,which is an extreme but facultative alkaliphile that grows non-fermentatively in a pH range from 7.5 to above 11.4.The Na+/H+ antiporter encoded by gene nhaC are sub-membrane transport protein distributed in the cell membrane, which play a key role in regulating cytoplasmic pH value by coupling net H+ uptake with Na+ extrusion.
 ===Usage and Biology===
 The gene nhaC from the Bacillus pseudofirmus OF4 encodes the Na+/H+ antiporter, which regulates cytoplasmic pH value by coupling net H+ uptake with Na+ extrusion. NhaC, the first demonstrated alkaliphile Na+/H+ antiporter, as part of a complement of antiporters in the wild-type alkaliphile, apparently plays a role over a wide range of pH values.