Difference between revisions of "Part:BBa K2486103"

Latest revision as of 17:29, 27 October 2017

Anti-malarial single-chain antibody m4B7 (no stop codon)

[theoretical part] [not assembled, not synthesized, not sent, not characterized]

Single chain antibody (scFvs) derived from mouse monoclonal antibodies, able to block Plasmodium falciparum, a malaria agent, in vivo.

GenBank: https://www.ncbi.nlm.nih.gov/nuccore/HQ315885

/Isaacs, Alison T., et al. "Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi." PLoS pathogens 7.4 (2011): e1002017

Sequence and Features

Assembly Compatibility:

10
INCOMPATIBLE WITH RFC[10]
Illegal EcoRI site found at 573
Illegal PstI site found at 676
12
INCOMPATIBLE WITH RFC[12]
Illegal EcoRI site found at 573
Illegal PstI site found at 676
Illegal NotI site found at 736
21
INCOMPATIBLE WITH RFC[21]
Illegal EcoRI site found at 573
Illegal XhoI site found at 435
23
INCOMPATIBLE WITH RFC[23]
Illegal EcoRI site found at 573
Illegal PstI site found at 676
25
INCOMPATIBLE WITH RFC[25]
Illegal EcoRI site found at 573
Illegal PstI site found at 676
1000
COMPATIBLE WITH RFC[1000]

@@ Line 7: / Line 7: @@
 Single chain antibody (scFvs) derived from mouse monoclonal antibodies, able to block Plasmodium falciparum, a malaria agent, in vivo.
+GenBank: https://www.ncbi.nlm.nih.gov/nuccore/HQ315885
 /Isaacs, Alison T., et al. "Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi." PLoS pathogens 7.4 (2011): e1002017