Difference between revisions of "Part:BBa K1893027"

Latest revision as of 19:53, 28 October 2016

3-isopropylmalate dehydrogenase (leuB)

This part encodes for 3-isopropylmalate dehydrogenase, an enzyme in the leucine biosynthesis pathway of Escherichia coli that catalyses the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate. The leucine biosynthesis pathway is activated in conditions of leucine starvation and can exploited for use in auxotrophy systems.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

Revision as of 14:33, 23 October 2016 (view source) HOLL579 (Talk \| contribs) ← Older edit		Latest revision as of 19:53, 28 October 2016 (view source) Cmoller (Talk \| contribs)
Line 3:		Line 3:
	<partinfo>BBa_K1893027 short</partinfo>		<partinfo>BBa_K1893027 short</partinfo>

−	~~leuB~~ encodes for 3-isopropylmalate dehydrogenase, an enzyme in the ~~biosynthetic~~ pathway of ~~leucine~~ that catalyses the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate. ~~This~~ is ~~different from (other leuB part)~~	+	This part encodes for 3-isopropylmalate dehydrogenase, an enzyme in the leucine biosynthesis pathway of Escherichia coli that catalyses the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate. The leucine biosynthesis pathway is activated in conditions of leucine starvation and can exploited for use in auxotrophy systems.