Difference between revisions of "Part:BBa K1729001"
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This translational unit includes the Kozak and codon-optimized sequence for the ''Saccharomyces cerevisiae'' [http://www.yeastgenome.org/locus/S000005319/overview ''MRPS12''] gene, which encodes a ribosomal protein of the small subunit of the mitochondrial ribosome. The coding sequence begins with a mitochondrial localization signal (MLS), which is presumably removed in the mitochondrion. The resultant protein is a homologue of the highly conserved uS12 ribosomal protein (Ban ''et al''.), which is essential for ribosome function. | This translational unit includes the Kozak and codon-optimized sequence for the ''Saccharomyces cerevisiae'' [http://www.yeastgenome.org/locus/S000005319/overview ''MRPS12''] gene, which encodes a ribosomal protein of the small subunit of the mitochondrial ribosome. The coding sequence begins with a mitochondrial localization signal (MLS), which is presumably removed in the mitochondrion. The resultant protein is a homologue of the highly conserved uS12 ribosomal protein (Ban ''et al''.), which is essential for ribosome function. | ||
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| + | The part sequence corresponds to nucleotides 694840-694361 on chromosome XIV of the ''S. cerevisiae'' S288C reference genome. | ||
[[File:MRPS12 Seq.jpg|900 px|]] | [[File:MRPS12 Seq.jpg|900 px|]] | ||
Revision as of 13:38, 18 September 2015
Yeast mitochondrial ribosomal protein MRPS12
This translational unit includes the Kozak and codon-optimized sequence for the Saccharomyces cerevisiae [http://www.yeastgenome.org/locus/S000005319/overview MRPS12] gene, which encodes a ribosomal protein of the small subunit of the mitochondrial ribosome. The coding sequence begins with a mitochondrial localization signal (MLS), which is presumably removed in the mitochondrion. The resultant protein is a homologue of the highly conserved uS12 ribosomal protein (Ban et al.), which is essential for ribosome function.
The part sequence corresponds to nucleotides 694840-694361 on chromosome XIV of the S. cerevisiae S288C reference genome.
References
Ban, Nenad et al. “A New System for Naming Ribosomal Proteins.” Current opinion in structural biology 24 (2014): 165–169.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 442
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]