Difference between revisions of "Part:BBa K1653003"
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ispA(from ''Escherichia coli'' JM109) | ispA(from ''Escherichia coli'' JM109) | ||
| − | ispA encodes geranyl diphosphate synthase | + | ispA encodes not only geranyl diphosphate synthase but also farnesyl diphosphate synthase. |
Farnesyl diphosphate synthase can utilize both dimethylallyl and geranyl diphosphates as substrates, generating geranyl and farnesyl diphosphate, respectively. Therefore the enzyme can catalyze two sequential reactions in the polyisoprenoid biosynthetic pathway. | Farnesyl diphosphate synthase can utilize both dimethylallyl and geranyl diphosphates as substrates, generating geranyl and farnesyl diphosphate, respectively. Therefore the enzyme can catalyze two sequential reactions in the polyisoprenoid biosynthetic pathway. | ||
Revision as of 10:41, 17 September 2015
ispA
ispA(from Escherichia coli JM109)
ispA encodes not only geranyl diphosphate synthase but also farnesyl diphosphate synthase.
Farnesyl diphosphate synthase can utilize both dimethylallyl and geranyl diphosphates as substrates, generating geranyl and farnesyl diphosphate, respectively. Therefore the enzyme can catalyze two sequential reactions in the polyisoprenoid biosynthetic pathway.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 867
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 163
- 1000COMPATIBLE WITH RFC[1000]