Difference between revisions of "Part:BBa K1391010"

Revision as of 02:12, 31 October 2014

pENTR_PirB

PirB (paired immunoglobin-like receptor B) is a transmembrane protein found in murine neurons, shown to bind to beta-amyloid. The interactions is mediated by the first two extracellular immunoglobulin (Ig) domains. Upon binding to beta-amyloid (extracellular), PirB induces enhanced cofilin signaling (intracellular).

Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.

The characterization of the system this is part of can be found in the experience page.

Sequence and Features

Assembly Compatibility:

10
INCOMPATIBLE WITH RFC[10]
Illegal EcoRI site found at 244
Illegal EcoRI site found at 1735
Illegal PstI site found at 1324
12
INCOMPATIBLE WITH RFC[12]
Illegal EcoRI site found at 244
Illegal EcoRI site found at 1735
Illegal PstI site found at 1324
21
INCOMPATIBLE WITH RFC[21]
Illegal EcoRI site found at 244
Illegal EcoRI site found at 1735
Illegal BamHI site found at 53
23
INCOMPATIBLE WITH RFC[23]
Illegal EcoRI site found at 244
Illegal EcoRI site found at 1735
Illegal PstI site found at 1324
25
INCOMPATIBLE WITH RFC[25]
Illegal EcoRI site found at 244
Illegal EcoRI site found at 1735
Illegal PstI site found at 1324
1000
INCOMPATIBLE WITH RFC[1000]
Illegal SapI.rc site found at 2062

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 __NOTOC__
 <partinfo>BBa_K1391010 short</partinfo>
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 Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.
+The characterization of the system this is part of can be found in the experience page.
 <!-- Add more about the biology of this part here