Difference between revisions of "Part:BBa K1420000"
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<p>''merB''</p> | <p>''merB''</p> | ||
| − | <p></p> | + | <p>The ''merB'' gene is often found immediately downstream of ''merA'', and is essential for the detoxification and bioremediation of organic toxic mercury compounds in congruence with ''merA''. The ''merB'' protein is a lyase that catalyzes the breaking of carbon-mercury bonds through protonolysis of toxic mercury compounds, such as methylmercury. This produces the less toxic and less mobile Hg<sup>2+</sup> which is then completely volatilized to Hg<sup>0</sup> when acted upon the enzyme ''merA''. (For more information on the ''merB'' gene, see part BBa_K1420002.)</p> |
Revision as of 05:05, 17 October 2014
Mer operon, biological system found to detoxify organic and inorganic forms of mercury
converts organomercuric and cationic mercury to the less toxic volatile mercury.
Components of the mer operon
merR
merT
merP
merA
merB
The merB gene is often found immediately downstream of merA, and is essential for the detoxification and bioremediation of organic toxic mercury compounds in congruence with merA. The merB protein is a lyase that catalyzes the breaking of carbon-mercury bonds through protonolysis of toxic mercury compounds, such as methylmercury. This produces the less toxic and less mobile Hg2+ which is then completely volatilized to Hg0 when acted upon the enzyme merA. (For more information on the merB gene, see part BBa_K1420002.)
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 551
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 2420
Illegal NgoMIV site found at 2468
Illegal NgoMIV site found at 2530
Illegal NgoMIV site found at 2741
Illegal NgoMIV site found at 3334 - 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI site found at 536