Difference between revisions of "Part:BBa K1151000"

(Usage and Biology)
(Usage and Biology)
Line 8: Line 8:
 
===Usage and Biology===
 
===Usage and Biology===
  
[[File:Cattura.jpg]]                                          [[File:Cattura1.jpg]]
+
                                                    [[File:Cattura.jpg]]                                           
  
'''Figure 1:''' HpNikR nickel-binding domain (tetramer).       '''Figure 2:''' Proteic sequence analysis with Uniprot.
+
                                    '''Figure 1:''' HpNikR nickel-binding domain (tetramer).                                                                    
 +
 
 +
 
 +
 
 +
 
 +
[[File:Cattura1.jpg]]
 +
 
 +
'''Figure 2:''' Proteic sequence analysis with Uniprot.
  
 
===Safety===
 
===Safety===

Revision as of 12:19, 26 September 2013

Nickel-responsive pleiotropic regulator (HpNikR)

The HpNikR protein is a pleiotropic regulator from Helicobacter pylori. In presence of nickel it can acts as an activator or a repressor depending of the specific promoter that contains its operator site. It consists of two dimeric DNA binding domains separated by a tetrameric regulatory domain that binds nickel. This domain corresponds to the C-terminal regulatory domain which contains four nickel binding sites at the tetramer interface. Binding nickel, then a conformational change allows it to activate or repress trascription.


Usage and Biology

                                                    Cattura.jpg                                           
                                   Figure 1: HpNikR nickel-binding domain (tetramer).                                                                     



Cattura1.jpg

Figure 2: Proteic sequence analysis with Uniprot.

Safety

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]