Difference between revisions of "Part:BBa K1151000"

(Usage and Biology)
(Usage and Biology)
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[[File:Cattura.jpg]]
 
[[File:Cattura.jpg]]
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HOLO-NI(II) HPNIKR TETRAMER.
 
HOLO-NI(II) HPNIKR TETRAMER.
  

Revision as of 11:51, 26 September 2013

Nickel-responsive pleiotropic regulator (HpNikR)

The HpNikR protein is a pleiotropic regulator from Helicobacter pylori. In presence of nickel it can acts as an activator or a repressor depending of the specific promoter that contains its operator site. It consists of two dimeric DNA binding domains separated by a tetrameric regulatory domain that binds nickel. This domain corresponds to the C-terminal regulatory domain which contains four nickel binding sites at the tetramer interface. Binding nickel, then a conformational change allows it to activate or repress trascription.


Usage and Biology

Cattura.jpg

HOLO-NI(II) HPNIKR TETRAMER.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]