Difference between revisions of "Part:BBa K1019004"

 
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<partinfo>BBa_K1019004 short</partinfo>
 
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"YdeH is a diguanylate cyclase that regulates motility and biofilm formation; its effect is probably mediated by the second messenger molecule c-di-GMP" (http://ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG11643)
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YdeH is a dyguanylate cyclase that is involved in producing the key secondary messenger c-di-GMP. c-di-GMP is propoed to be a "master regulator" of biofilm formation.
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Its expression increases surface adhesion and various aspects of the biofilm response.
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For further details and additional references please visit [http://ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG11643 EcoCyc]
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===References===
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Jonas, K., Edwards, A. N., Simm, R., Romeo, T., Römling, U., & Melefors, Ö. (2008). The RNA binding protein CsrA controls cyclic di‐GMP metabolism by directly regulating the expression of GGDEF proteins. Molecular microbiology, 70(1), 236-257.
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Boehm, A., Steiner, S., Zaehringer, F., Casanova, A., Hamburger, F., Ritz, D., ... & Jenal, U. (2009). Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress. Molecular microbiology, 72(6), 1500-1516.
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Steiner, S., Lori, C., Boehm, A., & Jenal, U. (2012). Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein–protein interaction. The EMBO journal.
  
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Its expression increases surface adhesion.
 
  
 
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<span class='h3bb'>Sequence and Features</span>
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===<span class='h3bb'>Sequence and Features</span>===
 
<partinfo>BBa_K1019004 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K1019004 SequenceAndFeatures</partinfo>
  

Revision as of 21:15, 27 September 2013

YdeH Diguanylate Cyclase

YdeH is a dyguanylate cyclase that is involved in producing the key secondary messenger c-di-GMP. c-di-GMP is propoed to be a "master regulator" of biofilm formation.

Its expression increases surface adhesion and various aspects of the biofilm response.

For further details and additional references please visit [http://ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG11643 EcoCyc]

References

Jonas, K., Edwards, A. N., Simm, R., Romeo, T., Römling, U., & Melefors, Ö. (2008). The RNA binding protein CsrA controls cyclic di‐GMP metabolism by directly regulating the expression of GGDEF proteins. Molecular microbiology, 70(1), 236-257.

Boehm, A., Steiner, S., Zaehringer, F., Casanova, A., Hamburger, F., Ritz, D., ... & Jenal, U. (2009). Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress. Molecular microbiology, 72(6), 1500-1516.

Steiner, S., Lori, C., Boehm, A., & Jenal, U. (2012). Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein–protein interaction. The EMBO journal.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 775
    Illegal SapI.rc site found at 800