Difference between revisions of "Part:BBa K1190000"

 
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<partinfo>BBa_K1190000 short</partinfo>
 
<partinfo>BBa_K1190000 short</partinfo>
  
 
Protein melan-A is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
 
Protein melan-A is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
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<img src="https://static.igem.org/mediawiki/parts/2/21/MelA_ov-seq.jpg">
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This parts has been sequence confirmed, quantitatively deonstrating correct identification of biobrick.
  
 
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Revision as of 10:42, 5 October 2013

Melan-A (MART-1)

Protein melan-A is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.

This parts has been sequence confirmed, quantitatively deonstrating correct identification of biobrick.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]