Difference between revisions of "Part:BBa K875009"
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The LL 37 cathelicidin is a human antimicrobial peptide.
 
The LL 37 cathelicidin is a human antimicrobial peptide.
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The antimicrobial peptides (AMPs) are present in all species investigated. They form an important part of innate immunity, protecting the organism from infection by directly killing invading bacteria. (Ulrich et al., 2006)
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The exact mechanism by which AMPs kill microorganisms is still under debate.
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It disrupts the bacteria membrane from outside and it is armless from inside. 
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The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression.  
 
The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression.  

Revision as of 14:39, 26 September 2012

LL 37 - Cathelicidin

The LL 37 cathelicidin is a human antimicrobial peptide.

The exact mechanism by which AMPs kill microorganisms is still under debate.

The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression.




Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]