Difference between revisions of "Part:BBa K875009"
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The LL 37 cathelicidin is a human antimicrobial peptide. | The LL 37 cathelicidin is a human antimicrobial peptide. | ||
| − | The antimicrobial peptides (AMPs) are present in all species investigated. They form an important part of innate immunity, protecting the organism from infection by directly killing invading bacteria. | + | The antimicrobial peptides (AMPs) are present in all species investigated. They form an important part of innate immunity, protecting the organism from infection by directly killing invading bacteria. (Ulrich et al., 2006) |
| − | It disrupts the bacteria membrane from outside and it is armless from inside. | + | It disrupts the bacteria membrane from outside and it is armless from inside. |
The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression. | The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression. | ||
Revision as of 14:57, 24 September 2012
LL 37 - Cathelicidin
The LL 37 cathelicidin is a human antimicrobial peptide. The antimicrobial peptides (AMPs) are present in all species investigated. They form an important part of innate immunity, protecting the organism from infection by directly killing invading bacteria. (Ulrich et al., 2006)
It disrupts the bacteria membrane from outside and it is armless from inside.
The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]