Difference between revisions of "Part:BBa K861051"
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FadR is a transcription regulator, which, when not binds to acyl-CoA can either serve as an activator for fatty acid synthesis gene like FabA, FabB and etc. or a repressor for fatty acid degradation gene like FadA, FadB, FadD and etc. After long chain fatty acid is converted into fatty acyl- CoA by FadD, it can bind to FadR. This binding will alter the conformation of FadR, making it unable to bind to the DNA sequence it recognizes. To our knowledge, there is no promoter exists in nature that can respond solely to FadR since those promoters are often regulated by glucose concentration or oxidative stress and many other factors. | FadR is a transcription regulator, which, when not binds to acyl-CoA can either serve as an activator for fatty acid synthesis gene like FabA, FabB and etc. or a repressor for fatty acid degradation gene like FadA, FadB, FadD and etc. After long chain fatty acid is converted into fatty acyl- CoA by FadD, it can bind to FadR. This binding will alter the conformation of FadR, making it unable to bind to the DNA sequence it recognizes. To our knowledge, there is no promoter exists in nature that can respond solely to FadR since those promoters are often regulated by glucose concentration or oxidative stress and many other factors. | ||
| − | This | + | This part contains a RBS and a terminator. |
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Latest revision as of 14:56, 22 September 2012
FadR with a RBS and a terminator
FadR is a transcription regulator, which, when not binds to acyl-CoA can either serve as an activator for fatty acid synthesis gene like FabA, FabB and etc. or a repressor for fatty acid degradation gene like FadA, FadB, FadD and etc. After long chain fatty acid is converted into fatty acyl- CoA by FadD, it can bind to FadR. This binding will alter the conformation of FadR, making it unable to bind to the DNA sequence it recognizes. To our knowledge, there is no promoter exists in nature that can respond solely to FadR since those promoters are often regulated by glucose concentration or oxidative stress and many other factors.
This part contains a RBS and a terminator.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]