Difference between revisions of "Part:BBa K339006"
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CpxP is a member of the Cpx regulon which docks on to CpxA, a transmembrane protein normally. But in the case of envelope stress causing protein misfolding in the periplasmic space, CpxP detaches from CpxA and attaches to the misfolded protein in the periplasmic space.
 
CpxP is a member of the Cpx regulon which docks on to CpxA, a transmembrane protein normally. But in the case of envelope stress causing protein misfolding in the periplasmic space, CpxP detaches from CpxA and attaches to the misfolded protein in the periplasmic space.
  
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<table>
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<td>
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http://i872.photobucket.com/albums/ab287/iGEMCalgary_2010/Cpxresponse.png</td>
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<td> This diagram illustrated that the CpxP promoter is the most sensitive in the stress regulon. CpxP is followed by CpxR and DegP respectively. These were selected because they are some of the most sensitive in the periplasmic stress detection pathways</td>
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</tr>
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</table>
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===Functional Parameters===
 
===Functional Parameters===
 
<partinfo>BBa_K339006 parameters</partinfo>
 
<partinfo>BBa_K339006 parameters</partinfo>

Revision as of 05:29, 30 October 2010

CpxP Promoter

CpxP promoter, periplasmic stress activated promoter

Usage and Biology

CpxP is a member of the Cpx regulon which docks on to CpxA, a transmembrane protein normally. But in the case of envelope stress causing protein misfolding in the periplasmic space, CpxP detaches from CpxA and attaches to the misfolded protein in the periplasmic space.

http://i872.photobucket.com/albums/ab287/iGEMCalgary_2010/Cpxresponse.png This diagram illustrated that the CpxP promoter is the most sensitive in the stress regulon. CpxP is followed by CpxR and DegP respectively. These were selected because they are some of the most sensitive in the periplasmic stress detection pathways

Functional Parameters